【摘要】目的 观察抑制PI3K/Akt信号通路对胶质瘤侵袭性及增殖力的影响。方法 制备对数生长期的胶质瘤细胞,设置对照组和实验组,空白对照组不进行药物处理,普通对照组经过药物顺铂
的侵袭性明显弱于DDP组:7267-7275.
[10]韦鹏翔.中国中西医实用神经外科学[M].2015,北京:中国医药科技出版社,2015:501-520.
[11]Habberstad AH, Lind-Landstrom T,Sundstorm S,et al.Primary human glioblastomas-prognostic value of clinical and histopathological parameters[J].Clin Neuropathol,2012,31:e1002.
[13]Brandes AA,Franceschi E,Tosoni A,et al.Epidermal growth factor receptor inhibitors in neuro-oncoloy:hopes and disappointments[J].Clin Cancer Res,2008,14:7548-7556.
[15]Hatanpaa KJ,Burma S,Zhao D,et al.Epidermal growth factor receptor in glioma:signal transduction,neuropathology,imaging,and radioresistance[J].Neoplasis,2010,12:1926-1933.
[17]董 倫,蒲佩玉,王 虎,等.EGFR反义RNA与p53基因联合转导抑制胶质瘤细胞增殖的体外实验研究[J].中华神经外科杂志,2007,23:678-681.
本文编辑:吴宏艳
查看全文
false